FGF-2, MMP-8 and Integrin α2β1 Expression in Periodontal ligament Remodelling Tension Area with Nanopowder <i>Stichopus hermanii</i> Application to Prevent Orthodontic Relapsing

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Occlusal stimuli regulate interleukin-1 beta and FGF-2 expression in rat periodontal ligament.

While many studies reported the structural changes in the periodontal ligament (PDL) under hypofunctional conditions, the associations of cytokine growth factors are still unclear. They are known to take part in inflammation, and may affect the biological properties of hypofunctional tooth. To investigate the hypofunctional PDL and the recovery from this condition, we focused on interleukin-1 b...

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Biological Events in Periodontal Ligament and Alveolar Bone Associated with Application of Orthodontic Forces

Orthodontic force-induced stresses cause dynamic alterations within the extracellular matrix and within the cytoskeleton of cells in the periodontal ligament and alveolar bone, mediating bone remodelling, ultimately enabling orthodontic tooth movement. In the periodontal ligament and alveolar bone, the mechanically induced tensile strains upregulate the expression of osteogenic genes resulting ...

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Periodontal regeneration and FGF-2

Periodontal diseases are highly prevalent inflammatory diseases that lead to a destruction of tooth-supporting tissues, such as the periodontal ligament, alveolar bone and cementum, and ultimately result in tooth loss. Conventional treatment for periodontal diseases is the mechanical removal of the periodontal biofilm, which although effective in reducing inflammation in lesion sites, dose not ...

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Immunolocalization of FGF-2 and VEGF in rat periodontal ligament during experimental tooth movement

OBJECTIVE This article aimed at identifying the expression of fibroblast growth factor-2 (FGF-2) and vascular endothelial growth factor (VEGF) in the tension and pressure areas of rat periodontal ligament, in different periods of experimental orthodontic tooth movement. METHODS An orthodontic force of 0.5 N was applied to the upper right first molar of 18 male Wistar rats for periods of 3 (gr...

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Expression and Presence of OPG and RANKL mRNA and Protein in Human Periodontal Ligament with Orthodontic Force

OBJECTIVE The objective of this study is to investigate the expression and concentration of ligand receptor activator of NFkB (RANKL) and osteoprotegerin (OPG) in human periodontal ligament (hPDL) with orthodontic forces of different magnitudes. METHODS Right premolars in 32 patients were loaded with 4oz or 7oz of orthodontic force for 7 days. Left first premolars were not loaded. After 7 day...

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ژورنال

عنوان ژورنال: International Journal of Materials Science and Applications

سال: 2017

ISSN: 2327-2635

DOI: 10.11648/j.ijmsa.20170606.13